Menu
Life Sciences
Baxter/Gambro Renal Products
CRB Architects
CRB Builders
230,000
A $300M expansion to the existing manufacturing facility producing hemodialysis dialyzers, a life-sustaining therapy for patients with end-stage renal disease.
The expansion incorporates space for every aspect of manufacturing, including receiving raw products, Dissolving, Distillation, ISO 8 Production Rooms, Injection Molding, Clean Rooms for Final Treatment, Sterilization of finished products, and Warehousing.
Mechanical systems include medium-pressure steam, low-pressure steam, clean steam, chilled water, condenser water, heating hot water, reverse osmosis, compressed air, process waste and vent, sanitary waste and vent, non-potable water, potable water, nitrogen, natural gas, fuel oil, and storm. A mechanical penthouse accommodates thirteen air handling units, a steam-to-hot water converter skid, and two clean steam generators.
Pharmavite
The Whiting-Turner Contracting Company
O’Brien/Atkins Associates, PA
330,000 sq. ft.
Pharmaceutical manufacturing plant of dietary supplements. The mechanical scope of work includes a 3,000-ton chiller plant, 900 Boiler HP steam plant, 500,000 CFM of conditioned air, Kathabar humidity control system, and 120,000 CFM dust collection system. Air rotation units provide another 120,000 CFM of ventilation to the warehouse areas.
The support for the manufacturing spaces includes central vacuum system, a central compressed air system, process systems including mineral oil, soybean oil, and glycerin; a central deionized water system;
The plumbing consists of a sanitary waste system to serve the restrooms and laboratories. Industrial waste serves the remainder of the building as is piped to a central below-grade dilution cistern.
Construction was scheduled at an accelerated pace with a start-to-finish duration of nine (9) months.
Visible Genetics Corporation
Kohl, Gramigna Architects, Inc.
Johnson, Spellman & Associates
Negotiated
Schoppman Freese Company
Office: 640
Laboratory: 30,442
The facility consists of two types of air handling systems: Constant volume (3 air handling units) and variable volume (5 air handling units), rooftop units with hot water reheat terminal units serving the offices and laboratories. There are two custom-built rooftop air handling units to serve the Class 100 and Class 10,000 cleanrooms with humidification and HEPA diffusers in the ceiling and HEPA filters in the air handling units.
The laboratories, cleanrooms, and PCR suites have independent pressure controls.
The support for the system includes two hot water boilers and two air-cooled chillers with a primary/secondary pumping system. The entire facility is DDC controlled and operated. It is monitored after hours with a digital pager receiving all alarms.
The plumbing consists of a sanitary waste system to serve the restrooms and laboratories. The laboratories have central domestic hot water, compressed air, natural gas, and D.I. water systems. All other gases are individually bottled in each laboratory.
Ethicon/ Johnson & Johnson
CRB Consulting Engineers, Inc.
CRB Consulting Engineers, Inc.
Gilbane Building Companies
Lump sum
80,517 Sq. Ft.
Mann Mechanical provided mechanical and plumbing contracting services for pharmaceutical manufacturing. 1,000 tons of chilled water is provided via a pair of water-cooled centrifugal VFD chillers. Steam was piped from the existing boiler plant to a skid-mounted hot water heat exchanger to provide heating to the facility. A rainwater harvesting system provides make-up water to the cooling towers. Eight (8) custom-fabricated roof-mounted air handling units condition the building for both temperature and humidity control. A separate, closed chilled water loop provides cooling to the manufacturing operations. Additional utility services to the manufacturing equipment included non-potable water, steam/condensate, compressed air, vacuum, and nitrogen. Over 12 miles of piping were installed while Mann Mechanical, as a member of the Gilbane team, completed the project within budget and on time.